Monday, December 30, 2013

Link found responsible for colon cancer initiation and metastasis

It was believed that the chronic inflammation was the key risk factor responsible for cancer that too particularly colon cancer. No doubt this notion was believed but still the exact mechanisms of how it affects human body were still unexplained. Also it was well understood that anti-inflammatory drugs including aspirin can reduce the risk of colorectal cancer. Now according to a very new study it has been found the reason for the growth of colon cancer. The researchers have seen the tumor formation, growth and progression in a mouse model of colon cancer. This research has provided new clues toward the prevention and treatment of colorectal cancer. The co-researcher, Dr. Ray DuBois, M.D., PhD, Biodesign Institute has shown that a key genetic culprit and explained it further, “We have been trying for the past several years to understand the precise molecular links between inflammation. We have demonstrated that CXCR2 mediates a critical step in the setup of the blood circulatory machinery that feeds tumor tissue. This provides an important new clue for the development of therapeutic targets to neutralize the effect of CXCR2 on colon cancer.”

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