Saturday, December 28, 2013
New Drug for Brain Tumor Can Distinguish Between Healthy and Cancer Infected Cells
Glioblastoma is the commonest form of brain tumor cells. Scientists from Cancer Research UK have been treating gliablastoma cells and healthy cells with 150 cancer drugs in the laboratory. It has been found that one molecule J101 stopped the growth of cancerous cells and left the healthy ones alone. It actually blocked poyo-like kinase 1 (Plk1), a cellular messaging molecule which tells cancer cells to grow.
It is being presumed that a fault in a gene called p53, which actually helps repair damaged DNA, could be the cause of gliablastoma.
Currently there are three drugs that are under preclinical and clinical trials that have been found to stop the growth of cancer cells. In fact they penetrate the blood stream of the brain better than J101. These might help develop distinctly different methods of treatment for different cancers. These lab based tests are paving the way for using these drugs on patients in the near future.
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