Saturday, January 25, 2014

New findings show a relation between alcohol consumption with hereditary cancer cell in genes

A research done by Kern and his team and published in the American Journal of Pathology reviewed the possibility of the affect of alcohol in individuals who has both the cancer triggering cells namely BRCA2 and PALB2. They say that these two cells protect cells against the damaging affects of acetaldehyde, which is found in alcohol. This chemical causes DNA damage. Studies show that BRCA2 and PALB2-mutant cell in individuals which were more exposed to acetaldehyde had 25 times more growth reduction in cancer cells when compared with similar cells which did not have these mutations. Kern goes on to say that acetaldehyde can be used to develop drugs which can kill cancer cells or at least alter their risks in humans. He says, "In most people, the genes function well and we're equipped to handle most of our exposure to acetaldehyde, but patients or carriers with mutations in these genes could face a higher risk of cancers with high exposure to alcohol or acetaldehyde-containing foods."

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