A study published in Nature was conducted by Dr. Daisuke Nakada and Dr. Hideyuki Oguro on the effect of oestrogen levels which affect production of blood forming stem cells. It is a well known fact the stem cells are controlled differently in male and female by respective hormones. The study which was done on mice models showed that the stem cells which result in blood formation divide faster in females than in males. This is triggered by the presence of oestrogen levels in the blood.
Both the male and female models were treated with doses of oestrogen so as to make them equivalent to what it reaches during pregnancy. It was seen that when the oestrogen receptor was removed from the cell, they stopped reacting to it. The red blood cell production also stopped. The study raises hope and increases the possibility of treating people who suffer from any kind of blood formation disease.
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