What concludes Single-patient trials is statin tolerability!
Based on the results of March 4 edition based on Annals of Internal Medicine Health Day special publication has mentioned that patients suffering from the problem of statin-connected myalgia, and single-patient inconstant trials of placebo and statin can decide if the myalgia is in fact occur because of the statin.
A managing director of Western University in London and Canada, Tisha R. Joy with his colleagues has conducted n-of-1 based trials on eight patients having statin-related myalgia. These patients were selected on random basis to get assigned placebo or statin for equal to three weeks, by means of three-week intervals washout.
Such researchers set up that for every patient there exist no major differences amid placebo or statin in conditions of visual analog scale myalgia score.
Joy and colleagues concluded "In selected patients with a history of statin-related myalgia whose symptoms are difficult to evaluate, n-of-1 trials may be a useful method for determining statin tolerability,”