Women carrying babies conceived with assisted reproductive technologies are more likely to suffer from a serious complications such as stillbirth, preterm birth, low birth weight and neonatal death, the results of a recent study show.
Scientists from the University of Adelaide's Robinson Institute, Australia, studied 17 years of data from more than 300,000 births in South Australia, among these births 4300 were the result of assisted reproduction.
Michael Davies, study leader and professor at the University of Adelaide's Robinson Institute, said in a statement, "Compared with spontaneous conceptions in couples with no record of infertility, singleton babies from assisted conception were almost twice as likely to be stillborn, more than twice as likely to be preterm, almost three times as likely to have very low birth weight, and twice as likely to die within the first 28 days of birth."
However the authors note that these outcomes varied depending on the type of assisted conception used. The study researchers found that Very low and low birth weight, very preterm and preterm birth, and neonatal death were markedly more common in births from IVF and, to a lesser degree, in births from ICS. Frozen embryos were also associated with increased risk of macrosomia or big baby syndrome for IVF and ICSI babies.
Prof Davies said the study confirmed earlier works which showed that infertility treatment is associated with adverse outcomes for newborn babies.
"More research is now urgently needed into longer term follow-up of those who have experienced comprehensive perinatal disadvantage," Prof Davies conclude.
The study was published in the journal PLOS ONE.
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