New approach to develop the induced pluripotent stem cells for in vivo disease modeling

As per a new research paper published in Cell Stem Cell has discovered a new approach by turning the induced pluripotent stem cells (iPSCs) towards the hematopoietic stem and progenitor cells for in vivo disease modeling. The researchers from the Boston Children's Hospital's Stem Cell Transplantation Program turned out this report. This is a progressive step with a real big advantage. Here the technique lies with the raw material. The team members started with iPSCs and had grown myeloid progenitors that are very closely related to the needed blood progenitors. The differentiated cells are usually used in the stem cell experiments. This has helped the researchers a lot. After the re-specification technique is a big help to generate the large number of engraftable cells. This is needed to create animal models and iPSCs generated from human patients those who are suffering from range of blood disorders including anemias, thalassemia or sickle cell disease.