Bumps roads leads to long-lasting, single-injection nerve blocks

According to a new research published in the journal Anesthesia & Analgesia, of the International Anesthesia Research Society suggested that the single injection of liposomal bupivacaine produced the femoral nerve block lasting much longer than the 24 hours. For this study, scientist took up fourteen healthy volunteers who were assigned single-injection blocks of the femoral nerve through the upper thigh using different doses of bupivacaine. Their responses were then studied on the terms of pain tolerance and the muscle movement. Through this the scientist concluded long lasting result in sensory and nerve block. One of the co-author, Dr Brian M. Ilfeld from University of California San Diego explains, “This inverse relationship is biologically implausible and most likely due to the limited sample size and the subjective nature of the measurement instruments. An alternative approach is to encapsulate a long-acting local anesthetic within microspheres or liposomes.”