Liver Enzyme CEH Helps Remove Bad Cholesterol from the Body

Professor of Internal Medicine Pulmonary Division of the Virginia Commonwealth School of Medicine Dr Shobha Ghosh, is leading a team of researchers who are trying to understand CEH. A key enzyme of the liver CEH regulates the removal of cholesterol from body cells. It also works with HDL or the good cholesterol. SR-B1 a membrane protein along with CEH helps drive cholesterol out of the body and enhance the influx of HDL into the bile. Dr Ghosh says that although the enzyme has been identified further study is required to understand how it is regulated and thereby how to enhance its activities through pharmacological means. Drugs developed to promote the activity of this enzyme will therefore reduce atherosclerosis, the deposit of cholesterol on the walls of arteries. Atherosclerosis is the main cause of heart disease or coronary artery in human beings.