Damaged DNA Can Cause Amyotrophic Lateral Sclerosis (ALS) Related Diseases

ALS is a disease that is caused due to neurons and there is no way to cure for such disease. The MIT research has found that if the DNA is unable to repair, then many other neurodegenerative diseases. Neuron is the main cause of DNA damage and other diseases. The Director of MIT Mr.Li-Huei found that if the machinery that repairs the DNA break down the neurons would be highly affected and thus can cause much dangerous disease. The director and his team are interested in understanding the importance of DNA repair in neurodegenerative mechanism. The team published that HDAC1 that is an enzyme work with another SIRT1 to repair the DNA and save from all the neurons related problems. SIRT1 contains proteins and helps fight against diseases. Tsai said that at early stage the FUS genes is able to cope up the problems related to DNA, but as time passes it contributes to neuron diseases.