Monday, January 27, 2014
Metastatic prostate cancer has a new powerful animal model developed
Cold Spring Harbor Laboratory has developed a new powerful animal model which creates better mouse models for metastatic prostate cancer. The discovery has a double role: from one hand, it enables new therapeutics to treat and from the other hand, it helps researchers to investigate. The results of the discovery are published in Cancer Discovery. The team of researchers was led by Associate Professor Lloyd Trotman.
The team of researchers discovered that prostate tumors lead to metastasize simply by Myc protein amount increase. Trotman worked on this study in collaboration with Professor James Brodner from Dana Farber.
“The RapidCaP system has revealed a specific role for Myc as a druggable driver of metastasis in prostate cancer”, says Trotman. “So there's hope that our model provides a fast and faithful test-bed for developing new approaches to cure the type of prostate cancer that today is incurable”.
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