Noninvasive 18F-fluoride PET can find culprit coronary plaques
According to a new study published in journal The Lancet suggests that the combined positron emission tomography (PET) and computed tomography (CT) are using the radioactive tracer 18F-sodium fluoride (18F-NaF), this can identify the ruptured and high-risk coronary plaques. This is a big advancement in field of science. This research can change the scenario.
For this research the team conducted a clinical trial with 40 patients having myocardial infarction and 40 of them with stable angina who underwent 18F-NaF and 18F-fluorodeoxyglucose (18F-FDG) PET-CT and invasive coronary angiography. Then there was a comparison of 18F-fluoride tissue-to-background ratios of culprit and non-culprit coronary plaques of patients with acute myocardial infarction was the primary end point.
The researchers further found that the highest coronary 18F-NaF uptake was observed in the culprit plaque median maximum tissue-to-background ratio: culprit, 1.66 versus highest non-culprit, 1.24 in the 93 per cent of the patients along with myocardial infarction.