As per a latest research conducted at the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee have found a new chemical messenger that is important in protecting the brain against Parkinson’s disease. They have made unexpected discovery about the paths of the two genes interact. This will open up new options for research around the Parkinson's and also offer new drug targets. The research could be read in Biochemical Journal. The research further shows that the phospho-ubiquitin functions directly to startle on the Parkin enzyme.
The co-researcher, Dr Muqit, a Wellcome Trust Senior Clinical Fellow and Consultant Neurologist at the MRC Protein Phosphorylation and Ubiquitylation Unit at Dundee explains, “Understanding the fundamental mechanisms of how brain cells die in Parkinson's is likely to uncover new insights into how to treat this progressive disorder. Our previous research had mapped out a key pathway involving the PINK1 and Parkin genes that when disrupted by mutations led to Parkinson's disease.”