The change in genetic material, shape leads to ALS linked gene that causes disease
The researchers of John Hopkins are of the view that they have got a way which was recently found as genetic mutation which may lead to two malicious nervous system ailments. Actually, the affected genes have the chance to build up toxic RNA and does not create required protein as per the reports. The main root of this problem is said to be the growls of imperfect genetic material which is created at the place of mutation.
Recently, the researchers and experts connected the gene C9orf72, mentioned its place on the 9th human chromosome to Amyotrophic lateral sclerosis, which is known as Lou Gehrig’s disease to Frontotemporal dementia.
It is said by Margaret Sutehrland, Ph.D., Program director at the National institute of Neurological Disorders and Stroke that, “The findings described in Dr. Wang’s paper open up a new pathogenic mechanism for ALS and FTD by providing insight into the biology associated with the C90rf72 mutation and identifying a potential path forward for therapy development.”