Friday, January 3, 2014

Ways offered by scientists to interrupt fibrosis

A group of scientists along with the researchers of Saint Louis University have found a new method to intervene in the cellular and molecular cascade which causes fibrosis. It is a condition in which the body’s usual process of outlining scars for healing of wounds goes into overdrive and this can cause diseases. According to the reports published in nature medicine, there is a possible novel therapeutic approach to care fibrotic diseases like liver fibroids and idiopathic pulmonary fibrosis. The researchers targeted a way that changes the major molecular mediator that causes fibrosis which is a protein known as Transforming Growth Factor beta. It is present in the body in a dull state and need to be changed on to form the basis for fibrosis. When activated this protein stimulates cell known as my fibroblasts in order to produce more collagen, a standard element of scars. According to David Griggs, Ph.D., Director of Biology at Saint Louis University’s Centre for world health and medicine and even and a author of the paper said that “This is the first foray into targeting not just a single integrin, but rather several integrins that appear to be working in concert to promote fibrosis.”

No comments:

Post a Comment