Drugs not helpful to reawaken dormant HIV infection
As per the scientists working at Johns Hopkins came forward with a harsh report. They were hoping that some specific compounds could turn as ‘wake up’ dormant reservoirs for the HIV inside immune system T cells. This was basically a plan designed to reverse the latency and then make the cells weak and then destroying it. Disappointingly the experiment turned out to be a failure. The research could formulate any compound to work in the direction. The report is published in Nature Medicine.
The co-researcher, Robert F. Siliciano, M.D., Ph.D., a professor of medicine at the Johns Hopkins University School of Medicine and a Howard Hughes Medical Institute explains, “Despite our high hopes, none of the compounds we tested in HIV-infected cells taken directly from patients activated the latent virus.” The disappointing result has given a new direction to the research now scientists are moving past it and working on new drugs.